For the source text click/tap here: Yevamot 49
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Rabbi Shimon ben Azay reports that he found a scroll in Jerusalem that accused King Menashe as having killed the prophet Yeshayahu.
Rava comments that that Menashe did not simply murder him, rather he put him on trial for heresies that appear among his prophecies.
Although Yeshayahu could explain each one of them, he chose not to do so, because he knew that Menashe would kill him in any case, and he preferred that Menashe should not be held responsible for murder.
We explore the midrashim and the apocryphal text of the Ascension of Isaiah that claims he was sawed in half when hiding in a cedar tree. This then passes on to Christian and Muslim traditions.
There is a tradition of martyrdom of prophets or which Isaiah is an early example.